Oral iloprost treatment in patients with Raynaud's phenomenon secondary to systemic sclerosis: A multicenter, placebo-controlled, double-blind study
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چکیده
منابع مشابه
Oral iloprost in Raynaud's phenomenon secondary to systemic sclerosis: a multicentre, placebo-controlled, dose-comparison study.
OBJECTIVE To identify the optimal dose of oral iloprost on the basis of efficacy and tolerability in patients with Raynaud's phenomenon secondary to systemic sclerosis. DESIGN Multicentre, randomized, parallel-group comparison of two different doses of oral iloprost and placebo. SETTING European university hospitals. PATIENTS A total of 103 patients with Raynaud's phenomenon secondary to ...
متن کاملTitle Oral iloprost as a treatment for Raynaud's syndrome: A double blind multicentre placebo controlled study
Objective-To compare the efficacy, tolerance and safety of 50-150 ,ug orally administered iloprost given twice a day versus placebo in patients with Raynaud's syndrome. Methods-The study was multicentre (n = 3), double blind and placebo controlled. Sixty three patients who had eight or more vasospastic attacks per week were enrolled. After a one week run-in period, all patients received either ...
متن کاملOral iloprost as a treatment for Raynaud's syndrome: a double blind multicentre placebo controlled study.
OBJECTIVE To compare the efficacy, tolerance and safety of 50-150 micrograms orally administered iloprost given twice a day versus placebo in patients with Raynaud's syndrome. METHODS The study was multicentre (n = 3), double blind and placebo controlled. Sixty three patients who had eight or more vasospastic attacks per week were enrolled. After a one week run-in period, all patients receive...
متن کاملComparison of intravenous infusions of iloprost and oral nifedipine in treatment of Raynaud's phenomenon in patients with systemic sclerosis: a double blind randomised study.
OBJECTIVE To compare the long term effects of short term intravenous infusions of iloprost with those of oral nifedipine in patients with Raynaud's phenomenon associated with systemic sclerosis. DESIGN Double blind, placebo controlled, randomised group comparison. SETTING Dermatology outpatient clinic. PATIENTS Twenty three patients with Raynaud's phenomenon associated with well documente...
متن کاملBosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study.
BACKGROUND Eisenmenger syndrome is characterized by the development of pulmonary arterial hypertension with consequent intracardiac right-to-left shunt and hypoxemia in patients with preexisting congenital heart disease. Because Eisenmenger syndrome is associated with increased endothelin expression, patients may benefit from endothelin receptor antagonism. Theoretically, interventions that hav...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1998
ISSN: 0004-3591,1529-0131
DOI: 10.1002/1529-0131(199804)41:4<670::aid-art14>3.0.co;2-i